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HSD17B13-IN-85

HSD17B13-IN-85 (186) is a potent small molecule inhibitor of 17β-Hydroxysteroid dehydrogenase 13 (HSD17B13), demonstrating an IC50 < 0.1 μM against estradiol. It is a valuable research tool for investigating the role of HSD17B13 in metabolic liver diseases, including nonalcoholic fatty liver disease (NAFLD), in both in vitro and in vivo studies.

Product Specifications

CAS Number

2770247-76-0

Field of Research

Metabolism Research

Smiles

N (C (=O) C1=CC (Cl) =C (O) C (Cl) =C1) C2=C3C (N=C (CF) N (CC4=C (C (F) (F) F) C=CC=C4) C3=O) =C (C) C=C2

Molecular Formula

C25H17Cl2F4N3O3

Molecular Weight

554.32

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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