HSD17B13-IN-85
HSD17B13-IN-85 (186) is a potent small molecule inhibitor of 17β-Hydroxysteroid dehydrogenase 13 (HSD17B13), demonstrating an IC50 < 0.1 μM against estradiol. It is a valuable research tool for investigating the role of HSD17B13 in metabolic liver diseases, including nonalcoholic fatty liver disease (NAFLD), in both in vitro and in vivo studies.
Product Specifications
CAS Number
2770247-76-0
Field of Research
Metabolism Research
Smiles
N (C (=O) C1=CC (Cl) =C (O) C (Cl) =C1) C2=C3C (N=C (CF) N (CC4=C (C (F) (F) F) C=CC=C4) C3=O) =C (C) C=C2
Molecular Formula
C25H17Cl2F4N3O3
Molecular Weight
554.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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