HSD17B13-IN-99
HSD17B13-IN-99 (Compound 6) is a potent small-molecule inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 <0.1 μM against estradiol. It is a valuable research tool for investigating the role of HSD17B13 in liver diseases such as NAFLD, NASH, and DILI in both cellular and animal models.
Product Specifications
CAS Number
2849338-46-9
Field of Research
Metabolism Research
Smiles
N (C (=O) C=1N=C (C (F) (F) F) C (O) =CC1) C2=C3C (N=CN (CCC4=C (OC) C=CC=C4) C3=O) =CC=C2
Molecular Formula
C24H19F3N4O4
Molecular Weight
484.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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