IDOR-1117-2520
IDOR-1117-2520 is a potent and selective CCR6 antagonist, inhibiting CCL20-induced calcium flux (IC50 63 nM) and β-arrestin recruitment (IC50 30 nM) . It is a valuable research tool for studying CCR6-mediated pathways in autoimmune diseases, such as psoriasis and rheumatoid arthritis, in both in vitro and in vivo models.
Product Specifications
CAS Number
2737274-49-4
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
99.93% (May vary between batches)
Smiles
[C@] (O) (C1 (C) CN (C) C1) (C=2C=C (C=NC2) C=3N=C (C (C) (C) O) ON3) C4=CC=C (C (C) C) C=C4
Molecular Formula
C25H32N4O3
Molecular Weight
436.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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