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IDOR-1117-2520

IDOR-1117-2520 is a potent and selective CCR6 antagonist, inhibiting CCL20-induced calcium flux (IC50 63 nM) and β-arrestin recruitment (IC50 30 nM) . It is a valuable research tool for studying CCR6-mediated pathways in autoimmune diseases, such as psoriasis and rheumatoid arthritis, in both in vitro and in vivo models.

Product Specifications

CAS Number

2737274-49-4

Field of Research

Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery

Purity

99.93% (May vary between batches)

Smiles

[C@] (O) (C1 (C) CN (C) C1) (C=2C=C (C=NC2) C=3N=C (C (C) (C) O) ON3) C4=CC=C (C (C) C) C=C4

Molecular Formula

C25H32N4O3

Molecular Weight

436.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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