IKZF1-degrader-1
Compound 9-B (IKZF1-degrader-1) is a highly potent small molecule degrader of the IKZF1 protein with a DC50 of 0.134 nM. It is a valuable research tool for studying IKZF1 biology and has demonstrated utility in preclinical models of hematological malignancies, supporting investigations into targeted protein degradation for oncology.
Product Specifications
CAS Number
2915586-02-4
Field of Research
Epigenetics & Chromatin, Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
C (C=1C=2C=3C (N (C (=O) C3C=C (F) C2) [C@@H]4C (=O) NC (=O) CC4) =CC1) C5=CC=C (CN6CCN (CC6) C7=C (F) C=C (C#N) C=C7) C=C5
Molecular Formula
C35H29F2N5O3
Molecular Weight
605.63
Storage Conditions
-20°C
Notes
For research use only.
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