ITF5924
ITF5924 is a highly selective and potent HDAC6 inhibitor (IC50 = 7.7 nM) featuring a difluoromethyl-1,3,4-oxadiazole moiety. It acts as a slow-binding substrate analog, forming a stable, long-lasting complex with the enzyme after catalytic ring opening. This inhibitor is a valuable chemical tool for probing HDAC6 function in oncology and neurology research models.
Product Specifications
CAS Number
2760854-72-4
Field of Research
Epigenetics & Chromatin, Molecular Biology
Smiles
C (N1C=C (N=N1) C2=CC=C (NC=3NCCN3) C=C2) C4=CC=C (C=C4) C=5OC (C (F) F) =NN5
Molecular Formula
C21H18F2N8O
Molecular Weight
436.42
Storage Conditions
-20°C
Notes
For research use only.
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