JAB-2485
JAB-2485 is a highly selective AURKA inhibitor (IC50 = 0.33 nM) with >1000-fold selectivity over AURKB. It is a valuable research tool for studying mitotic progression, cell cycle arrest, and apoptosis in cancer models, applicable in both in vitro and in vivo experimental settings.
Product Specifications
CAS Number
2899209-55-1
Field of Research
Cell Biology, Epigenetics & Chromatin
Smiles
C ([C@]1 (C (O) =O) C[C@@H] (C) N (CC2=C (F) C (Cl) =CC=C2) CC1) C=3N=C (NC=4NN=C (C) C4) C (F) =C (C) C3
Molecular Formula
C25H28ClF2N5O2
Molecular Weight
503.97
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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