JAB-2485
JAB-2485 is a highly selective AURKA inhibitor (IC50 = 0.33 nM) with >1000-fold selectivity over AURKB. It is a valuable research tool for studying mitotic progression, cell cycle arrest, and apoptosis in cancer models, applicable in both in vitro and in vivo experimental settings.
Product Specifications
CAS Number
2899209-55-1
Field of Research
Cell Biology, Epigenetics & Chromatin
Smiles
C ([C@]1 (C (O) =O) C[C@@H] (C) N (CC2=C (F) C (Cl) =CC=C2) CC1) C=3N=C (NC=4NN=C (C) C4) C (F) =C (C) C3
Molecular Formula
C25H28ClF2N5O2
Molecular Weight
503.97
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
248623-Biotin 100 µL
MECP2 (methyl CpG Binding Protein 2 (Rett Syndrome), AUTSX3, DKFZp686A24160, MRX16, MRX79, MRXS13, MRXSL, PPMX, RTS, RTT) (Biotin)
Sign In for Pricing
View Details 
K1851-01X-APC 100 µL
Kip2, p57 (cdk Inhibitor, Cyclin Dependent Kinase Inhibitor) (BSA & Azide Free) (APC) discontinued
Sign In for Pricing
View Details 
K6072903 1.0 µg DNA
Vom2r49 sgRNA CRISPR Lentivector (Rat) (Target 2)
Sign In for Pricing
View Details K3932802 1.0 µg DNA
Nkx2-6 sgRNA CRISPR Lentivector (Mouse) (Target 1)
Sign In for Pricing
View Details 
36260111 3x 1.0 µg
PDCD1LG2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
Sign In for Pricing
View Details K3780904 1.0 µg DNA
Eral1 sgRNA CRISPR Lentivector (Mouse) (Target 3)
Sign In for Pricing
View Details