JAK1-IN-12
JAK1-IN-12 is a potent and selective JAK1 inhibitor with an IC50 of 24.6 nM, showing significant selectivity over JAK2, JAK3, and TYK2. This compound has demonstrated efficacy in promoting hair growth in mouse models, supporting its use in research for immune, inflammatory, and dermatological conditions.
Product Specifications
CAS Number
2945204-95-3
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
N ([C@@H]1[C@@]2 (CC3 (O) C[C@@]1 (CC (C2) C3) [H]) [H]) C=4C (=CN=C5C4C=CN5) C=6C=NNC6
Molecular Formula
C20H23N5O
Molecular Weight
349.43
Storage Conditions
-20°C
Notes
For research use only.
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