JAK1-IN-13
JAK1-IN-13 (compound 36b) is a potent and highly selective oral JAK1 inhibitor with a 0.044 nM IC50, effectively suppressing STAT3 phosphorylation. It is a valuable research tool for investigating JAK1-dependent pathways in autoimmune and inflammatory disease models, both in vitro and in vivo.
Product Specifications
CAS Number
2778330-90-6
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
N (C1=C2C (=NC=C1C (NC) =O) NC=C2) [C@@H]3C[C@H] (C) N (CC4=CC=C (C (F) (F) F) C=C4) CC3
Molecular Formula
C23H26F3N5O
Molecular Weight
445.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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