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JAK3/BTK-IN-7

XL-12 (JAK3/BTK-IN-7) is a potent dual inhibitor of JAK3 (IC50=2 nM) and BTK (IC50=14 nM) . It is a research tool for investigating autoimmune and inflammatory diseases, including rheumatoid arthritis, in both cellular and animal models.

Product Specifications

CAS Number

2844387-16-0

Field of Research

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Smiles

NC1=C2C (=NN (C2=NC=N1) [C@H]3CN (C (C=C) =O) CCC3) C4=C5C (=C (NC (=O) C6=CC=C (N (C) C) C=C6) C=C4) OCO5

Molecular Formula

C29H30N8O4

Molecular Weight

554.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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