LAH-1
LAH-1 is a cell-permeable, orally bioavailable small molecule inhibitor of c-Met, demonstrating potent activity with an IC50 of 49 nM. It exerts anticancer effects by promoting apoptosis and inhibiting cell migration and invasion in vitro, supporting its investigation in oncology research for targeting c-Met-driven tumor progression.
Product Specifications
CAS Number
3018150-68-7
Field of Research
Cell Biology, Signal Transduction
Smiles
O=C1N (N=C (C (NC2=CC (F) =C (OC=3C=C (NC (=O) N4CC (O) C4) N=CC3) C=C2) =O) C (C) =C1) C5=CC=C (F) C=C5
Molecular Formula
C27H22F2N6O5
Molecular Weight
548.5
Storage Conditions
-20°C
Notes
For research use only.
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