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LC-MB12

LC-MB12 is an orally bioavailable, selective PROTAC degrader of FGFR2 with demonstrated antiproliferative and antitumor activity. It is a research tool for studying FGFR2 signaling in contexts such as gastric cancer, supported by in vitro and in vivo experimental data.

Product Specifications

CAS Number

2828438-38-4

Product Name Alternative

FGFR2, LCMB12, PROTAC

Field of Research

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Purity

99.16% (May vary between batches)

Solubility

DMSO:120 mg/mL (133.37 mM)

Smiles

O=C (NC=1C (Cl) =C (OC) C=C (OC) C1Cl) N (C=2N=CN=C (C2) NC3=CC=C (C=C3) N4CCN (C (=O) C5CCN (C6=CC=C7C (=O) N (C (=O) C7=C6) C8C (=O) NC (=O) CC8) CC5) CC4) C

Molecular Formula

C43H44Cl2N10O8

Molecular Weight

899.78

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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