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LL320

LL320 is a potent and selective small molecule inhibitor of nicotinamide N-methyltransferase (NNMT) with an apparent Ki of 6.8 nM. It also demonstrates activity against RNMT, DPH5, and SAHH, making it a useful chemical probe for investigating methylation-dependent pathways in metabolic and cancer research, both in vitro and in vivo.

Product Specifications

CAS Number

2672496-32-9

Smiles

O[C@H]1[C@H] (N2C=3C (N=C2) =C (N) N=CN3) O[C@H] (CN (CC#CC4=CC (C (N) =O) =CC=C4) CC[C@@H] (C (O) =O) N) [C@H]1O

Molecular Formula

C24H28N8O6

Molecular Weight

524.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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