LRRK2-IN-12
LRRK2-IN-12 is a highly potent and selective inhibitor of LRRK2, demonstrating sub-nanomolar IC50 values against both wild-type and the G2019S mutant kinase. This research compound is a valuable tool for in vitro and in vivo studies investigating the role of LRRK2 in neurodegenerative pathways, including Alzheimer's disease research.
Product Specifications
CAS Number
3032733-05-1
Field of Research
Cell Biology
Smiles
ClC=1C2=C3N (N1) CCCOC=4C (N=C (N3) N=C2) =C (C) N (N4) C5=C (OC) N=CC=C5
Molecular Formula
C18H17ClN8O2
Molecular Weight
412.83
Storage Conditions
-20°C
Notes
For research use only.
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