METTL1-WDR4-IN-2
METTL1-WDR4-IN-2 (compound 6) is a selective inhibitor of the METTL1-WDR4 methyltransferase complex with an IC50 of 41 μM. It exhibits significant selectivity over METTL3-METTL14 and modest selectivity against METTL16. This tool compound is used in vitro to investigate the role of m7G tRNA modification in cancer and stem cell biology.
Product Specifications
CAS Number
2919742-07-5
Field of Research
Epigenetics & Chromatin, Signal Transduction
Smiles
O[C@H]1[C@H] (N2C=3C (N=C2) =C (N) N=CN3) O[C@H] (CSCC4=CC (=CC (C (O) =O) =C4) C5=CC=C (O) C=C5) [C@H]1O
Molecular Formula
C24H23N5O6S
Molecular Weight
509.53
Storage Conditions
-20°C
Notes
For research use only.
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