MK-8457
MK-8457 is a potent and selective small molecule dual inhibitor of SYK and ZAP70 kinases. It is a valuable research tool for investigating autoimmune pathways, particularly in rheumatoid arthritis, and has been utilized in both in vitro cellular assays and in vivo disease models.
Product Specifications
CAS Number
1312518-84-5
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
O[C@]1 (CC (C) (C) [C@@H] (C (O) =O) CC1) C=2SC (=CN2) C3=CC (NC=4N=C (C (F) (F) F) C=CN4) =CC (C) =C3
Molecular Formula
C24H25F3N4O3S
Molecular Weight
506.54
Storage Conditions
-20°C
Notes
For research use only.
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