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MK-8527

MK-8527 is an orally bioavailable nucleoside reverse transcriptase translocation inhibitor (NRTTI) for HIV-1 research. It is metabolized intracellularly to its active triphosphate form, demonstrating potent antiviral activity with an IC50 of 0.21 nM in vitro. This small molecule is a valuable tool for investigating antiviral mechanisms and efficacy in both cellular and animal model studies.

Product Specifications

CAS Number

1810869-23-8

Product Name Alternative

MK8527

Field of Research

Immunology & Inflammation, Infectious Disease & Virology, Protein Biochemistry

Purity

99.15% (May vary between batches)

Solubility

DMSO:90 mg/mL (291.53 mM)

Smiles

NC1=C2C (N (C=C2) [C@@H]3O[C@] (C#C) (CO) [C@@H] (O) C3) =NC (Cl) =N1

Molecular Formula

C13H13ClN4O3

Molecular Weight

308.72

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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