MK-8527
MK-8527 is an orally bioavailable nucleoside reverse transcriptase translocation inhibitor (NRTTI) for HIV-1 research. It is metabolized intracellularly to its active triphosphate form, demonstrating potent antiviral activity with an IC50 of 0.21 nM in vitro. This small molecule is a valuable tool for investigating antiviral mechanisms and efficacy in both cellular and animal model studies.
Product Specifications
CAS Number
1810869-23-8
Product Name Alternative
MK8527
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Protein Biochemistry
Purity
99.15% (May vary between batches)
Solubility
DMSO:90 mg/mL (291.53 mM)
Smiles
NC1=C2C (N (C=C2) [C@@H]3O[C@] (C#C) (CO) [C@@H] (O) C3) =NC (Cl) =N1
Molecular Formula
C13H13ClN4O3
Molecular Weight
308.72
Storage Conditions
-20°C
Notes
For research use only.
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