ML-T7
ML-T7 is a potent Tim-3 inhibitor that blocks interactions with PtdSer and CEACAM1. It enhances the antitumor function of CTLs, CAR T cells, and NK cells in vitro and improves dendritic cell antigen presentation. This compound demonstrates efficacy in preclinical tumor models, supporting its investigation as a monotherapy or combined with checkpoint inhibitors like Nivolumab.
Product Specifications
CAS Number
459789-75-4
Field of Research
Immunology & Inflammation
Smiles
O=C1C2 (C3C (C (O2) C4=CC=C (C) C=C4) C (=O) N (C3=O) C5=C (Cl) C=C (Cl) C=C5) C (=O) C=6C1=CC=CC6
Molecular Formula
C27H17Cl2NO5
Molecular Weight
506.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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