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Nav1.7 blocker 1

Nav1.7 blocker 1 (example 41) is a potent small-molecule inhibitor of voltage-gated sodium channels, demonstrating an IC50 of 37 nM. It is a valuable research tool for studying neuropathic, inflammatory, and postoperative pain mechanisms in both cellular assays and animal models.

Product Specifications

CAS Number

1426336-36-8

Field of Research

Pharmacology & Drug Discovery

Smiles

C (O) C1N (C2=NC (=NC (C (N) =O) =C2) C3=CC=C (OC4=CC=C (F) C=C4) C=C3) CCOC1

Molecular Formula

C22H21FN4O4

Molecular Weight

424.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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