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NJK14047

NJK14047 is a p38 MAPK inhibitor that suppresses the differentiation of naive T-cells into pro-inflammatory Th1 and Th17 subsets. This mechanism underlies its efficacy in ameliorating murine models of collagen-induced arthritis and Imiquimod-induced psoriasis, supporting its use in autoimmune disease research.

Product Specifications

CAS Number

1800576-41-3

Field of Research

Signal Transduction

Smiles

CC=1C (=CC (C (NC2CC2) =O) =CC1) C3=CC=C (C (=O) C4=CC=C (OCC (CO) O) C=C4) C=C3

Molecular Formula

C27H27NO5

Molecular Weight

445.51

Storage Conditions

-20°C

Notes

For research use only.

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