NJK14047
NJK14047 is a p38 MAPK inhibitor that suppresses the differentiation of naive T-cells into pro-inflammatory Th1 and Th17 subsets. This mechanism underlies its efficacy in ameliorating murine models of collagen-induced arthritis and Imiquimod-induced psoriasis, supporting its use in autoimmune disease research.
Product Specifications
CAS Number
1800576-41-3
Field of Research
Signal Transduction
Smiles
CC=1C (=CC (C (NC2CC2) =O) =CC1) C3=CC=C (C (=O) C4=CC=C (OCC (CO) O) C=C4) C=C3
Molecular Formula
C27H27NO5
Molecular Weight
445.51
Storage Conditions
-20°C
Notes
For research use only.
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