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NLRP3-IN-28

NLRP3-IN-28 (N77) is a potent and selective NLRP3 inflammasome inhibitor, demonstrating an EC50 of 0.07 μM against nigericin-induced pyroptosis in vitro. It is a valuable research tool for studying NLRP3-driven pathologies, including inflammatory diseases, in both cellular and animal models.

Product Specifications

CAS Number

2922814-80-8

Field of Research

Cell Biology, Immunology & Inflammation

Smiles

OC1=C (C2=CC=C (S (C) (=O) =O) N=N2) C=CC (C (F) (F) F) =C1

Molecular Formula

C12H9F3N2O3S

Molecular Weight

318.27

Storage Conditions

-20°C

Notes

For research use only.

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