WK500B
WK500B is a cell-permeable BCL6 inhibitor that disrupts the BCL6 repression complex, reactivating target genes to induce apoptosis and cell cycle arrest in DLBCL cells. It demonstrates efficacy in both in vitro assays and in vivo models, inhibiting germinal center formation and tumor growth with favorable pharmacokinetics.
Product Specifications
CAS Number
2253985-29-2
Smiles
N (C1=NC (=NC=C1F) N2C[C@H] (C) N[C@H] (C) C2) C3=CC=C (NC (=O) C=4N=C (Br) C=CC4) C=C3
Molecular Formula
C22H23BrFN7O
Molecular Weight
500.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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