YD-3
YD-3 is a PAR4 antagonist that inhibits thrombin-induced platelet aggregation (IC50=28.3 μM in rabbits) and VSMC proliferation via Ras/ERK pathways, reducing neointimal thickening in vivo. It suppresses thrombin-induced Flk-1 expression and is a useful tool for studying thrombin-driven angiogenesis and vascular remodeling.
Product Specifications
CAS Number
170632-41-4
Field of Research
Protein Biochemistry
Smiles
O=C (OCC) C=1C=CC (=CC1) C2=NN (C=3C=CC=CC23) CC=4C=CC=CC4
Molecular Formula
C23H20N2O2
Molecular Weight
356.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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