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UNC8969

UNC8969 is a potent and selective macrocyclic dual inhibitor of MERTK and AXL with low nanomolar IC50 values. It demonstrates favorable pharmacokinetics and has shown significant anti-tumor efficacy in cellular models of lung cancer, supporting its utility in oncology research for studying TAM receptor signaling in vitro and in vivo.

Product Specifications

CAS Number

3036049-17-6

Field of Research

Signal Transduction

Smiles

CC1=CC=C (N2) C=C1OC/C=C\CNC3=NC2=C (C (N[C@@H]4CC[C@@H] (C (NCCN (CC) CC) =O) CC4) =O) C=N3

Molecular Formula

C29H41N7O3

Molecular Weight

535.68

Storage Conditions

-20°C

Notes

For research use only.

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