YT 6-2
ATC-324 is an AUTOTAC degrader that utilizes the autophagy-targeting ligand YT 6-2 to engage p62/SQSTM1, leading to the autophagic-lysosomal degradation of androgen receptor (AR) and its mutants. It effectively reduces nuclear AR levels and suppresses AR-driven gene expression, showing utility in prostate cancer research both in vitro and in vivo.
Product Specifications
CAS Number
2409959-90-4
Field of Research
Pharmacology & Drug Discovery
Smiles
O (CC1=CC=C (F) C=C1) C2=C (OCC3=CC=C (F) C=C3) C=CC (OC[C@@H] (CNCCO) O) =C2
Molecular Formula
C25H27F2NO5
Molecular Weight
459.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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