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O-Desmethylcarvedilol

O-Desmethylcarvedilol, an active metabolite of carvedilol, is a research compound that inhibits pathological calcium release via RyR2 (IC50=7.62 μM in vitro) and demonstrates in vivo efficacy by modulating heart rate and blood pressure responses to β-adrenergic stimulation in conscious animal models.

Product Specifications

CAS Number

72956-44-6

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Smiles

OC=1C=CC=CC1OCCNCC (O) COC2=CC=CC=3NC=4C=CC=CC4C23

Molecular Formula

C23H24N2O4

Molecular Weight

392.45

Storage Conditions

-20°C

Notes

For research use only.

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