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HP211206

HP211206 is a PROTAC-based degrader of SARS-CoV-2 Mpro (main protease), including resistant mutants, with an IC50 of 181.9 nM and a DC50 of 621 nM. It demonstrates antiviral activity and serves as a valuable chemical tool for studying coronavirus protease function and degradation mechanisms in both in vitro and cellular research.

Product Specifications

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery

Molecular Formula

C42H55F2N9O10

Molecular Weight

883.94

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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