Cetagliptin
Cetagliptin is a DPP-4 and CYP2D6 inhibitor (IC50 = 6 μM) that acts as a P-glycoprotein substrate. It is used in diabetes research to study mechanisms of glycemic control by preserving incretin hormones like GLP-1 in both in vitro and in vivo models.
Product Specifications
CAS Number
2243737-33-7
Field of Research
Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Protein Biochemistry
Smiles
P (=O) (O) (O) O.C (F) (F) (F) C=1N2C ([C@@H] (C) N (C (C[C@@H] (CC3=C (F) C=C (F) C (F) =C3) N) =O) CC2) =CN1
Molecular Formula
C18H21F6N4O5P
Molecular Weight
518.35
Storage Conditions
-20°C
Notes
For research use only.
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