CENTA

CENTA is a colorimetric cephalosporin substrate for β-lactamases. Upon hydrolysis by β-lacatamases, CENTA turns from light yellow to chrome yellow, which can be quantified by colorimetric detection at 405 nm as a measure of β-lactamase activity.

Product Specifications

CAS Number

[80072-86-2]

UNSPSC

12352005

Target

Beta-lactamase

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/centa.html

Purity

99.0

Smiles

O=C(O)C(N1[C@@]([H])([C@@H](C1=O)NC(CC2=CC=CS2)=O)SC3)=C3CSC4=CC=C(C(C(O)=O)=C4)[N+]([O-])=O

Molecular Formula

C21H17N3O8S3

Molecular Weight

535.57

References & Citations

[1]Jones, et al. In vitro evaluation of CENTA, a new beta-lactamase-susceptible chromogenic cephalosporin reagent. J. Clin. Microbiol. 15 (5), 954-958 (1982) .