NLRP3-IN-61
NLRP3-IN-61 is a potent and selective NLRP3 inflammasome inhibitor, suppressing pyroptosis (IC50=12.6 nM) and IL-1β release (IC50=25.3 nM) in THP-1 cells. It is a valuable research tool for studying NLRP3-driven pathologies, including inflammatory and autoimmune diseases, in cellular models.
Product Specifications
CAS Number
3060585-94-3
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
OC=1C (C=2N=C3C (OC (=N3) [C@@H]4CCC (=O) NC4) =CC2) =C (C) C=C5C1CCC5
Molecular Formula
C21H21N3O3
Molecular Weight
363.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K3041803 1.0 µg DNA
Gm5886 sgRNA CRISPR Lentivector (Mouse) (Target 2)
Sign In for Pricing
View Details 
orb3074617 100 µg
Growth Hormone/GH1 Rabbit Polyclonal Antibody (Fluoro594)
Sign In for Pricing
View Details