NLRP3-IN-61
NLRP3-IN-61 is a potent and selective NLRP3 inflammasome inhibitor, suppressing pyroptosis (IC50=12.6 nM) and IL-1β release (IC50=25.3 nM) in THP-1 cells. It is a valuable research tool for studying NLRP3-driven pathologies, including inflammatory and autoimmune diseases, in cellular models.
Product Specifications
CAS Number
3060585-94-3
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
OC=1C (C=2N=C3C (OC (=N3) [C@@H]4CCC (=O) NC4) =CC2) =C (C) C=C5C1CCC5
Molecular Formula
C21H21N3O3
Molecular Weight
363.41
Storage Conditions
-20°C
Notes
For research use only.
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