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YT 6-2-PEG3-C2-NH2

YT 6-2-PEG3-C2-NH2 is a key component in constructing the AUTOTAC degrader ATC-324, which targets the androgen receptor (AR) for autophagic degradation via the p62/SQSTM1 pathway. This mechanism, validated in prostate cancer research models, effectively reduces nuclear AR levels and suppresses the expression of AR and its splice variant AR-v7.

Product Specifications

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Molecular Formula

C33H44F2N2O8

Molecular Weight

634.71

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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