Clofarabine-5'-triphosphate
Clofarabine-5'-triphosphate, the active phosphorylated metabolite of the anticancer agent Clofarabine, is generated intracellularly by deoxycytidine kinase. It functions as a potent inhibitor of DNA synthesis and repair, making it a critical tool for studying nucleotide metabolism and cytotoxicity in leukemia and solid tumor research, both in vitro and in vivo.
Product Specifications
CAS Number
134646-41-6
Field of Research
Cell Biology, Molecular Biology, Pharmacology & Drug Discovery
Smiles
F[C@@H]1[C@H] (N2C=3C (N=C2) =C (N) N=C (Cl) N3) O[C@H] (COP (OP (OP (=O) (O) O) (=O) O) (=O) O) [C@H]1O
Molecular Formula
C10H14ClFN5O12P3
Molecular Weight
543.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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