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P-gp inhibitor 27

P-gp inhibitor 27 (Compound D2) is a small molecule that suppresses P-glycoprotein and MRP1 expression. It enhances Rh123 accumulation in resistant A2780/T cells and effectively reverses multidrug resistance to Paclitaxel and Cisplatin in vitro, with an EC50 of 88 nM against Paclitaxel.

Product Specifications

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Molecular Formula

C25H25N3O4

Molecular Weight

431.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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