AKT-IN-25
AKT-IN-25 (Compound 14a) is a potent Akt inhibitor that blocks its phosphorylation, disrupting the PI3K/Akt/mTOR pathway. It induces G1 phase cell cycle arrest, inhibits migration, and suppresses proliferation in pancreatic cancer cell lines PANC-1, PATU-T, and SUIT-2, with IC50 values ranging from 1.32 to 3.85 μM. This inhibitor is a valuable tool for studying oncogenic signaling in vitro.
Product Specifications
CAS Number
1619929-59-7
Field of Research
Signal Transduction
Smiles
O=C (N1N=NC (=C1) C=2C=CC=CC2) N3CCCCC3
Molecular Formula
C14H16N4O
Molecular Weight
256.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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