NW16
NW16 is an orally bioavailable STAT3 inhibitor (Kd = 11.0 μM) that exhibits potent anti-proliferative activity in vitro against HCT116, A549, and B16 cancer cells. It induces S-phase arrest, apoptosis, and ROS production while suppressing the PI3K/AKT pathway, and has demonstrated in vivo antitumor efficacy in mouse models.
Product Specifications
Field of Research
Cell Biology, Immunology & Inflammation, Signal Transduction, Stem Cell & Developmental Biology
Molecular Formula
C18H12N2O5
Molecular Weight
336.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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