Antiproliferative agent-64
Antiproliferative agent-64 is a potent small molecule inhibitor of eIF4E that disrupts mRNA secondary structure to block translation. It selectively targets oncogenic mRNAs like c-Myc (EC50=1.2 nM) and inhibits proliferation in MDA-MB-231 breast cancer cells (EC50=7 nM), supporting its use in cancer research and translational studies.
Product Specifications
CAS Number
1139263-21-0
Field of Research
Cell Biology, Molecular Biology, Signal Transduction
Smiles
O[C@]12[C@] ([C@@H] ([C@@H] (C (N (C) C) =O) [C@H]1O) C3=CC=CC=C3) (OC=4C2=C (OC) C=C (OC) C4) C5=CC=C (C#N) C=C5
Molecular Formula
C29H28N2O6
Molecular Weight
500.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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