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ZG-2033

ZG-2033 (Compound 26) is a potent, orally bioavailable HIF-2α agonist with an EC50 of 490 nM in cellular reporter assays. It demonstrates anti-anemic activity in vivo and exhibits synergistic effects with other HIF-PH inhibitors like AKB-6548, making it a valuable research tool for investigating renal anemia and hypoxia signaling pathways.

Product Specifications

CAS Number

2685739-28-8

Field of Research

Epigenetics & Chromatin, Metabolism Research

Smiles

N=1SC=2C=CC=CC2C1NC=3C=C (OC) C=C (OC) C3

Molecular Formula

C15H14N2O2S

Molecular Weight

286.35

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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