ZG-2033
ZG-2033 (Compound 26) is a potent, orally bioavailable HIF-2α agonist with an EC50 of 490 nM in cellular reporter assays. It demonstrates anti-anemic activity in vivo and exhibits synergistic effects with other HIF-PH inhibitors like AKB-6548, making it a valuable research tool for investigating renal anemia and hypoxia signaling pathways.
Product Specifications
CAS Number
2685739-28-8
Field of Research
Epigenetics & Chromatin, Metabolism Research
Smiles
N=1SC=2C=CC=CC2C1NC=3C=C (OC) C=C (OC) C3
Molecular Formula
C15H14N2O2S
Molecular Weight
286.35
Storage Conditions
-20°C
Notes
For research use only.
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