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GGFG-PAB-Exatecan TFA

GGFG-PAB-Exatecan TFA is a drug-linker conjugate designed for antibody-drug conjugate (ADC) synthesis, combining the potent topoisomerase I inhibitor Exatecan with a cleavable GGFG-PAB linker. This construct is utilized in research for developing targeted cancer therapies and has been evaluated in both in vitro and in vivo preclinical studies.

Product Specifications

Field of Research

Immunology & Inflammation; Pharmacology & Drug Discovery, Molecular Biology

Smiles

NCC (NCC (N[C@@H] (CC1=CC=CC=C1) C (NCC (NC (C=C2) =CC=C2COC (N[C@@H]3C4=C5C (C (N6C5) =CC ([C@] (O) (C (OC7) =O) CC) =C7C6=O) =NC8=CC (F) =C (C) C (CC3) =C84) =O) =O) =O) =O) =O.O=C (O) C (F) (F) F

Molecular Formula

C49H48F4N8O12

Molecular Weight

1016.95

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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