Nrf2 activator 18
Nrf2 activator 18 (Compound 11a) is an orally bioavailable small molecule that activates the Keap1/Nrf2/HO-1 pathway, leading to Nrf2 nuclear translocation and antioxidant response. It inhibits IL-6 release (IC50 = 4.816 μM) and has shown anti-inflammatory efficacy in a murine model of PM2.5-induced lung injury.
Product Specifications
Field of Research
Immunology & Inflammation
Molecular Formula
C23H24FN3O
Molecular Weight
377.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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