(R) -AS-1
(R) -AS-1 is a potent, selective positive allosteric modulator of EAAT2 (EC50 = 11 nM) . It exhibits anticonvulsant efficacy in multiple mouse seizure models (MES, PTZ) and enhances locomotor activity, supporting its research application in studying EAAT2 function and neurological disorders like epilepsy.
Product Specifications
CAS Number
2506367-95-7
Field of Research
Metabolism Research
Smiles
[C@H] (C (NCC1=CC=CC=C1) =O) (C) N2C (=O) CCC2=O
Molecular Formula
C14H16N2O3
Molecular Weight
260.29
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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