Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

JBJ-07-149

JBJ-07-149 is a potent, selective inhibitor of the EGFRL858R/T790M mutant (IC50 = 1.1 nM) . It demonstrates anti-proliferative activity in Ba/F3 cells, with efficacy significantly enhanced in combination with Cetuximab. This compound is also a key chemical precursor for synthesizing the PROTAC molecule [DDC-01-163], supporting targeted protein degradation research.

Product Specifications

CAS Number

2140807-58-3

Field of Research

Cardiovascular Research, Signal Transduction

Smiles

O=C1C2=CC (=CC=C2CN1C (C (=O) NC3=NC=CS3) C=4C=CC=CC4) C=5C=NC (=CC5) N6CCNCC6

Molecular Formula

C28H26N6O2S

Molecular Weight

510.61

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

KIAA0513 (NM_001297766) Human Tagged ORF Clone
RC237313 10 µg

KIAA0513 (NM_001297766) Human Tagged ORF Clone

Sign In for Pricing
View Details
Per2 sgRNA CRISPR Lentivector (Rat) (Target 2)
K6891003 1.0 µg DNA

Per2 sgRNA CRISPR Lentivector (Rat) (Target 2)

Sign In for Pricing
View Details
Rabbit Polyclonal RDH11 Antibody [Alexa Fluor 647]
NBP2-27584AF647 0.1 mL

Rabbit Polyclonal RDH11 Antibody [Alexa Fluor 647]

Sign In for Pricing
View Details
Research Grade Solrikitug
DHJ36107 100 μg

Research Grade Solrikitug

Sign In for Pricing
View Details
XFD647 Anti-human CD71 Antibody *HI166*
10711181-AAT 500 Tests

XFD647 Anti-human CD71 Antibody *HI166*

Sign In for Pricing
View Details
Cobalt (II) Oxide AR (71% Co)
00837 00100 100 g

Cobalt (II) Oxide AR (71% Co)

Sign In for Pricing
View Details