Isosorbide dinitrate
Isosorbide dinitrate (ISDN) is an NO donor that prevents LV remodeling and degradation of cardiac function following myocardial infarction (MI) [1].
Product Specifications
CAS Number
87-33-2
Product Name Alternative
ISDN
UNSPSC
12352005
Hazard Statement
H302, H312, H319
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/isosorbide-dinitrate.html
Purity
99.89
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
[H][C@]12OC[C@H](O[N+]([O-])=O)[C@]1(OC[C@H]2O[N+]([O-])=O)[H]
Molecular Formula
C6H8N2O8
Molecular Weight
236.14
Precautions
H302, H312, H319
References & Citations
[1]Wang X , et al. Intratracheal administration of isosorbide dinitrate improves pulmonary artery pressure and ventricular remodeling in a rat model of heart failure following myocardial infarction. Exp Ther Med. 2017 Aug;14 (2) :1399-1408.|[2]Zhao X, et al. Cardioprotective Effect of Isosorbide Dinitrate Postconditioning Against Rat Myocardial Ischemia-Reperfusion Injury In Vivo. Med Sci Monit. 2019 Mar 2;25:1629-1636.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
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