Thalidomide-NH-C2-2-azaspiro[3.3]heptane
This bifunctional compound is a conjugate of a thalidomide-based E3 ligase ligand and a 2-azaspiro[3.3]heptane linker, designed for synthesizing the PROTAC molecule KT-413. It serves as a key intermediate for research into targeted protein degradation, applicable in both in vitro and in vivo studies for oncology and immunology.
Product Specifications
CAS Number
2573305-00-5
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C1NC (=O) C (N2C (=O) C=3C=CC=C (NCCC4CC5 (CNC5) C4) C3C2=O) CC1
Molecular Formula
C21H24N4O4
Molecular Weight
396.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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