WRN inhibitor 17
WRN inhibitor 17 (Compound 250) is an orally bioavailable small molecule that selectively targets the helicase domain of Werner syndrome ATP-dependent helicase (WRN) . This inhibitor is a valuable research tool for investigating WRN's role in microsatellite unstable (MSI) cancers, with utility in both in vitro and in vivo preclinical studies.
Product Specifications
CAS Number
3064599-40-9
Field of Research
Cell Biology, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Molecular Biology
Smiles
C (O) (=O) [C@@H]1[C@H] (C[C@@H] (COC) C[C@H]1C (NC2=C (F) C=C (C (F) (F) F) C=C2) =O) C3=CC=C (N (S (=O) (=O) C=4C=C5C (=CC4) N (C) C (C) =N5) C) C=C3
Molecular Formula
C33H34F4N4O6S
Molecular Weight
690.71
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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