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AAK1/HDACs-IN-1

AAK1/HDACs-IN-1 (Compound 12) is a potent dual inhibitor of AAK1, HDAC1, and HDAC6 with IC50 values of 15.9, 148.6, and 5.2 nM, respectively. It has demonstrated antiviral activity in vitro by inhibiting SARS-CoV-2 entry through disruption of clathrin-mediated endocytosis, making it a useful research tool for studying viral infection pathways and epigenetic regulation.

Product Specifications

Field of Research

Epigenetics & Chromatin, Infectious Disease & Virology, Molecular Biology, Neuroscience

Molecular Formula

C21H14N4O2

Molecular Weight

354.36

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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